Skip to main content
. 2023 Nov 28;9(12):e22592. doi: 10.1016/j.heliyon.2023.e22592

Table 1.

IC50 Values (μM) and Selectivity Index of Cancer Cell Lines Treated With Compounds (6a-f) for 96 h.


Drug/cell line
IC50
SI
HDF U87 MCF-7 A549 U87 MCF-7 A549
6c 293.6 ± 11.4 12.29 ± 5.5 61.56 ± 11.1 238.8 ± 7.9 23.9 4.8 1.2
6d 425.2 ± 18.5 3.817 ± 2.9 123.5 ± 10.6 307.6 ± 12.1 111.4 3.4 1.4
6b 170.7 ± 8.1 1.2 ± 0.8 10.58 ± 2.3 29.4 ± 6.2 142.3 16.1 5.8
6a 504.2 ± 19.9 34.57 ± 7.8 112 ± 10.1 138.6 ± 9.3 14.6 4.5 3.6
6e 83 ± 5.8 45 ± 7.1 58.6 ± 5.9 79 ± 4.7 1.8 1.4 1.1
6f 141.7 ± 4.1 7.9 ± 2.3 10.6 ± 3 103.7 ± 4.5 18 13.3 1.4
Cisplatin 40.9 ± 5.4 28.3 ± 5.3 26.9 ± 4.7 30.4 ± 5.2 1.5 1.5 1.3