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. 2023 Dec 6;14:1302322. doi: 10.3389/fendo.2023.1302322

Table 4.

Areas under the receiver operating characteristic curves, 95%CI, best threshold, sensitivity and specificity for ALT, AST and GGT identifies NAFLD risk for all participants, females and males.

AUC 95%CI Best threshold Specificity Sensitivity
All participants (N=14,251)
 ALT 0.83 (0.82-0.84) 19.50 0.74 0.77
 AST 0.69* (0.68-0.70) 19.50 0.72 0.56
 GGT 0.77* (0.76-0.78) 17.50 0.72 0.70
Female (N=6,840)
 ALT 0.77 (0.74-0.79) 17.50 0.80 0.59
 AST 0.63* (0.61-0.66) 18.50 0.72 0.47
 GGT 0.72* (0.70-0.75) 12.50 0.61 0.74
Male (N=7,411)
 ALT 0.79 (0.78-0.80) 23.50 0.75 0.69
 AST 0.67* (0.66-0.68) 20.50 0.71 0.54
 GGT 0.70* (0.69-0.72) 20.50 0.66 0.66

AUC, area under the receiver operating characteristic curve; CI, confidence interval; other abbreviations as in Table 1 .

*P<0.05, compare with ALT.