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Characteristics of macrophage subtypes.
| Classification | M1 macrophages | M2 macrophages |
|---|---|---|
| Inducing factor | TH1 cytokine (IFN-γ,LPS,TNF-α，GM-CSF) | TH2 cytokines (IL-4,IL-10,IL-13) |
| Defining markers | iNOS, CD16/32, CD80, CD68 CD86, MHC II |
CD206，CD163，Arg1,Fizz1,YM1 |
| Chemokines | CCL19,CCL20, CXCL9,CXCL10, CXCL11,CXCL13 | CCL13,CCL14, CCL1,CCL20, CXCL1 |
