Fig. 5.

Deletion of Phlpp1 within Col1a1‐Cre expressing cells alters bone microarchitecture. Male (n = 9) and female (n = 8) Phlpp1 cKOCola1 mice and their control littermates (n = 10 males and females) were aged to 12 weeks. Shown are 2D reconstructions of (A) control and (B) Phlpp1 cKOCol1a1 females. Micro‐CT of the distal femora was performed, and (C) bone volume per total volume (BV/TV), (D) bone surface per total volume (BS/TV), (E) bone surface per bone volume (BS/BV), (F) trabecular thickness (Tb.Th), (G) trabecular number (Tb.N), and (H) trabecular spacing (Tb.Sp) were evaluated. The p values are as shown.