Table 2.
Comparison of the differences between groups.
| Beinaglutide | P value | Control | P value | P value | |||
|---|---|---|---|---|---|---|---|
| Baseline | 6-month | Baseline | 6-month | ||||
| FBG (mmol/L) | 7.47 ± 1.77 | 6.67 ± 1.90 | 0.02 | 7.86 ± 2.16 | 6.90 ± 2.17 | <0.01 | <0.01 |
| 2hBG (mmol/L) | 12.94 ± 2.23 | 8.02 ± 1.72 | <0.01 | 13.26 ± 2.63 | 10.34 ± 2.99 | 0.38 | <0.01 |
| HbA1c% | 9.45 (7.70,11.22) | 6.87 (4.90,8.25) | <0.01 | 9.60 (8.10,11.91) | 6.87 (5.29,8.79) | <0.01 | 0.86 |
| LBGI | 2.62 ± 1.81 | 2.12 ± 0.94 | 0.03 | 2.71 ± 1.20 | 2.52 ± 1.16 | 0.22 | <0.01 |
| Weight (kg) | 84.34 ± 13.86 | 79.30 ± 12.92 | 0.039 | 83.12 ± 16.09 | 85.39 ± 15.94 | 0.65 | <0.01 |
| BMI (kg/m2) | 27.08 ± 3.64 | 26.08 ± 2.89 | 0.029 | 26.87 ± 2.94 | 27.40 ± 2.87 | 0.56 | <0.01 |
| WC (cm) | 98.15 ± 9.67 | 93.62 ± 9.64 | 0.086 | 97.44 ± 8.29 | 98.38 ± 8.00 | 0.86 | <0.01 |
| SFA (cm2) | 175.96 ± 37.47 | 171.34 ± 40.30 | 0.63 | 171.86 ± 39.49 | 172.64 ± 41.66 | 0.99 | 0.07 |
| LMI (kg/m2) | 19.08 ± 2.87 | 20.08 ± 1.79 | 0.92 | 19.87 ± 3.56 | 1840 ± 2.87 | 0.58 | 0.77 |
| ALT (U/L) | 26.67 (19.96,37.15) | 25.46 (17.79,37.63) | 0.81 | 23.00 (17.00,37.12) | 23.03 (16.24,34.71) | 0.80 | 0.52 |
| AST (U/L) | 26.57 (19.00,35.00) | 27.37 (17.73,35.17) | 0.77 | 23.00 (17.00,33.00) | 22.89 (17.08,33.33) | 0.73 | 0.64 |
| Cr (mmol/L) | 70.82 ± 21.43 | 60.47 ± 22.36 | 0.092 | 69.16 ± 20.68 | 67.53 ± 21.38 | 0.35 | 0.07 |
| UA (mmol/L) | 364.96 ± 87.96 | 357.61 ± 81.49 | 0.55 | 357.29 ± 91.75 | 359.34 ± 82.29 | 0.76 | 0.28 |
| Non-fasting TG (mmol/L) | 2.74 ± 5.96 | 1.67 ± 3.50 | <0.01 | 2.68 ± 5.61 | 2.64 ± 5.27 | 0.84 | <0.01 |
| TC (mmol/L) | 4.96 (4.33,6.10) | 4.41 (3.79,5.67) | 0.08 | 4.96 (4.10,6.47) | 4.45 (3.56,5.72) | 0.13 | 0.78 |
| HDL-C (mmol/L) | 1.00 ± 0.24 | 1.17 ± 0.23 | <0.01 | 1.04 ± 0.22 | 1.23 ± 0.21 | <0.01 | 0.88 |
| LDL-C (mmol/L) | 2.93 ± 0.85 | 2.58 ± 0.78 | 0.05 | 2.85 ± 0.84 | 2.53 ± 0.76 | 0.07 | 0.28 |
| TG (mmol/L) | 2.12 (1.23,2.91) | 1.61 (0.98,2.61) | 0.08 | 2.24 (1.23,3.08) | 2.16 (1.27,2.91) | 0.72 | <0.01 |
| ApoB (mg/dL) | 1.01 ± 0.41 | 0.96 ± 0.38 | 0.62 | 1.02 ± 0.36 | 1.02 ± 0.36 | 0.99 | 0.34 |
| FFA (nmol/L) | 0.42 ± 0.20 | 0.40 ± 0.20 | 0.61 | 0.39 ± 0.17 | 0.38 ± 0.16 | 0.96 | 0.57 |
| HOMA-IR | 2.40 (1.16,3.23) | 2.03 (1.25,3.49) | 0.04 | 2.41 (1.19,3.19) | 2.95 (1.11,2.95) | 0.03 | <0.01 |