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. 2023 Dec 6;14:1267503. doi: 10.3389/fendo.2023.1267503

Table 2.

Comparison of the differences between groups.

Beinaglutide P value Control P value P value
Baseline 6-month Baseline 6-month
FBG (mmol/L) 7.47 ± 1.77 6.67 ± 1.90 0.02 7.86 ± 2.16 6.90 ± 2.17 <0.01 <0.01
2hBG (mmol/L) 12.94 ± 2.23 8.02 ± 1.72 <0.01 13.26 ± 2.63 10.34 ± 2.99 0.38 <0.01
HbA1c% 9.45 (7.70,11.22) 6.87 (4.90,8.25) <0.01 9.60 (8.10,11.91) 6.87 (5.29,8.79) <0.01 0.86
LBGI 2.62 ± 1.81 2.12 ± 0.94 0.03 2.71 ± 1.20 2.52 ± 1.16 0.22 <0.01
Weight (kg) 84.34 ± 13.86 79.30 ± 12.92 0.039 83.12 ± 16.09 85.39 ± 15.94 0.65 <0.01
BMI (kg/m2) 27.08 ± 3.64 26.08 ± 2.89 0.029 26.87 ± 2.94 27.40 ± 2.87 0.56 <0.01
WC (cm) 98.15 ± 9.67 93.62 ± 9.64 0.086 97.44 ± 8.29 98.38 ± 8.00 0.86 <0.01
SFA (cm2) 175.96 ± 37.47 171.34 ± 40.30 0.63 171.86 ± 39.49 172.64 ± 41.66 0.99 0.07
LMI (kg/m2) 19.08 ± 2.87 20.08 ± 1.79 0.92 19.87 ± 3.56 1840 ± 2.87 0.58 0.77
ALT (U/L) 26.67 (19.96,37.15) 25.46 (17.79,37.63) 0.81 23.00 (17.00,37.12) 23.03 (16.24,34.71) 0.80 0.52
AST (U/L) 26.57 (19.00,35.00) 27.37 (17.73,35.17) 0.77 23.00 (17.00,33.00) 22.89 (17.08,33.33) 0.73 0.64
Cr (mmol/L) 70.82 ± 21.43 60.47 ± 22.36 0.092 69.16 ± 20.68 67.53 ± 21.38 0.35 0.07
UA (mmol/L) 364.96 ± 87.96 357.61 ± 81.49 0.55 357.29 ± 91.75 359.34 ± 82.29 0.76 0.28
Non-fasting TG (mmol/L) 2.74 ± 5.96 1.67 ± 3.50 <0.01 2.68 ± 5.61 2.64 ± 5.27 0.84 <0.01
TC (mmol/L) 4.96 (4.33,6.10) 4.41 (3.79,5.67) 0.08 4.96 (4.10,6.47) 4.45 (3.56,5.72) 0.13 0.78
HDL-C (mmol/L) 1.00 ± 0.24 1.17 ± 0.23 <0.01 1.04 ± 0.22 1.23 ± 0.21 <0.01 0.88
LDL-C (mmol/L) 2.93 ± 0.85 2.58 ± 0.78 0.05 2.85 ± 0.84 2.53 ± 0.76 0.07 0.28
TG (mmol/L) 2.12 (1.23,2.91) 1.61 (0.98,2.61) 0.08 2.24 (1.23,3.08) 2.16 (1.27,2.91) 0.72 <0.01
ApoB (mg/dL) 1.01 ± 0.41 0.96 ± 0.38 0.62 1.02 ± 0.36 1.02 ± 0.36 0.99 0.34
FFA (nmol/L) 0.42 ± 0.20 0.40 ± 0.20 0.61 0.39 ± 0.17 0.38 ± 0.16 0.96 0.57
HOMA-IR 2.40 (1.16,3.23) 2.03 (1.25,3.49) 0.04 2.41 (1.19,3.19) 2.95 (1.11,2.95) 0.03 <0.01