TABLE 1.

Overview of group 5 pulmonary hypertension with unclear and/or multifactorial mechanisms

5.1) Haematological disorders

Inherited and acquired chronic haemolytic anaemias:

Sickle cell disease

β-thalassaemia

Spherocytosis

Stomatocytosis

Autoimmune disorders

Chronic myeloproliferative disorders:

Chronic myelogenous leukaemia

Polycythaemia vera

Idiopathic myelofibrosis

Essential thrombocytopenia

Others

5.2) Systemic disorders

Sarcoidosis

Pulmonary Langerhans's cell histiocytosis

Neurofibromatosis type 1

5.3) Metabolic disorders

Glycogen storage diseases and Gaucher disease

5.4) Chronic renal failure with or without haemodialysis

5.5) Pulmonary tumour thrombotic microangiopathy

5.6) Fibrosing mediastinitis