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. 2023 Dec 7;114(6):e2023048. doi: 10.23749/mdl.v114i6.14946

Table 2.

Detection limit of asbestos fiber’s type and technology used.

Technology used Chrysotile LOD* Amphibole LOD* Reference Cronological Order
TEM with SAED ** ** Patel-Mandlik, 1981 [16]
TEM with EDX 0.04 0.04 Huang et al., 1988 [9]
STEM with EDS 0.076 (control group) 0.076 (control group) Ehrlich et al., 1991 [10]
0.95 (exposed group) 0.95 (exposed group)
TEM with EDS 0.02 0.02 Molinini et al., 1992 [18]
SEM 0.1 0.1 Tossavainen et al., 1994 [17]
TEM with EDS 0.006 0.006 Pollice et al., 1995 [19]
TEM with EDS 0 0 Pollice et al., 1997 [14]
SEM with EDX 0.063 0.063 Muller et al., 2001 [12]
TEM with EDX 0.05 0.02 Uibu et al., 2009 [20]
SEM and EDS 3 3 Croce et al., 2018 [15]
SEM with EDS 0.03 (Healthy tissue)
0.08 (Neoplastic tissue)
0.03 (Healty tissue)
0.08 (Neoplastic tissue)
Rinaudo et al., 2021 [13]

* Limit of Detection (mfgdt): When the DL was not specified the lowest value observed was reported.

** The article reports, “If no fibers were observed in ten grid openings of two grids prepared from 100 mg dry weight of tissue, the value of F/mg dry weight would be Below Detection (BD) level.”

TEM=Transmission electron microscope, SAED=Selected area electron diffraction, EDX=Energy Dispersive X-ray Analysis.

EDS=Energy dispersive X-ray spectroscopy, SEM=Scanning electron microscope, ATEM=Analytical Transmission electron microscope.

STEM: Scanning Trasmission Electron Microscopy