Table 2.
Overall Sample |
Group-Wise Comparisons |
|||||
---|---|---|---|---|---|---|
Variable | Mean (SD) | Range | Control | MCI | Dementia | p |
Age, y | 71.8 (9.8) | 38–91 | 63.6 (10.4) | 71.9 (8.7) | 76.9 (7.6) | < 0.001 |
Sex, %F | 50.7 | 74.1 | 50.0 | 37.2 | 0.011 | |
Education, y | 15.9 (2.6) | 6–20 | 16.6(2.1) | 15.8 (2.6) | 15.9 (2.6) | 0.299 |
Race/Ethnicity | ||||||
% Non-Hispanic White | 95.6 | 96.2 | 95.5 | 96.2 | 0.986 | |
% Hispanic | 5.1 | 7.4 | 4.5 | 4.7 | 0.838 | |
APOE4 carrier, % | 39.8 | 26.1 | 36.2 | 38.9 | 0.583 | |
FAQ | 4.2 (5.9) | 0–24 | 0.1 (0.3) | 2.7 (3.8) | 8.9 (7.3) | < 0.001 |
NPI | 4.8 (4.9) | 0–27 | 1.4 (2.1) | 4.3 (3.9) | 7.8 (5.9) | < 0.001 |
Charlson | 2.2 (1.7) | 0–8 | 0.7 (0.1) | 2.4 (1.5) | 2.8 (0.3) | < 0.001 |
Hachinski | 0.9 (1.3) | 0–8 | 0.4 (0.6) | 0.9 (1.5) | 1.0 (1.4) | 0.180 |
Fried Frailty | 1.9 (1.3) | 0–5 | 0.8 (0.9) | 1.9 (1.3) | 2.5 (1.3) | < 0.001 |
MoCA | 21.9 (4.5) | 5–30 | 26.3 (2.6) | 22.9 (2.9) | 17.6(3.8) | < 0.001 |
CDR-SB | 2.1 (1.9) | 0–7 | 0.2 (0.2) | 1.4 (0.8) | 4.2 (1.8) | < 0.001 |
Mean (SD) or %. Bold signifies significance after Bonferroni correction (corrected p = 0.0038). FAQ, Functional Activities Questionnaire; NPI, Neuropsychiatric Inventory; MoCA, Montreal Cognitive Assessment; CDR-SB, Clinical Dementia Rating Sum of Boxes; MCI, mild cognitive impairment.