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. Author manuscript; available in PMC: 2023 Dec 20.
Published in final edited form as: J Alzheimers Dis. 2021;84(2):723–736. doi: 10.3233/JAD-210328

Table 6.

Comparison of Cognitive Performance by GCL + IPL Thickness Cut-off

Variable GCL + IPL
< 75 μm
(n = 64)
CGL + IPL
≥75 μm
(n = 72)
p
MoCA 20.3 (3.9) 23.7 (4.3) < 0.001
Numbers Forward 6.4 (1.4) 7.1 (1.3) 0.006
Numbers Backward 4.5 (1.2) 4.9 (1.5) 0.053
HVLT-Immediate 15.7 (5.3) 18.9 (6.2) 0.001
HVLT-Delay 4.1 (3.3) 6.3 (3.5) < 0.001
Trail making A, s 44.6 (19.9) 36.4 (22.6) 0.028
Trail making B, s 118.8 (48.2) 92.6 (44.3) 0.002
Number Symbol Coding 31.8 (11.2) 40.6 (11.8) < 0.001
Animal Naming 15.4 (5.6) 17.9 (5.6) 0.011
MINT 14.4 (0.9) 14.2 (2.1) 0.377
Z-Score −0.05 (0.8) 0.57 (0.7) < 0.001
CDR-SB 2.7 (1.9) 1.3 (1.6) < 0.001

Mean (SD). Bold signifies significance after correction for multiple comparisons (corrected p < 0.0042). GCL, ganglion cell layer; IPL, internal plexiform layer; MoCA, Montreal Cognitive Assessment; HVLT, Hopkins Verbal Learning Test; MINT, Multilingual Naming Test; CDR-SB, Clinical Dementia Rating Sum of Boxes.