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. Author manuscript; available in PMC: 2023 Dec 20.
Published in final edited form as: J Alzheimers Dis. 2021;84(4):1563–1576. doi: 10.3233/JAD-215020

Table 4.

Comparison of medical history by racial/ethnic groups in cluster 1 (Older age, Low SES)

Variable White
(n = 23)
African American
(n = 17)
Hispanic
(n = 68)
ANOVA
p
Post-hoc comparison p
W versus AA W versus H H versus AA
Age, y 72.6 (7.6) 77.1 (8.0) 72.7 (8.0) 0.171
Hollingshead SES 35.8 (15.3) 51.8 (15.8) 54.1 (17.2) <0.001 0.016 <0.001 0.882
Education, y 14.1 (2.2) 10.9 (3.0) 9.4 (3.6) <0.001 0.105 <0.001 0.021
Sex, % Female 43.5 58.8 83.8 <0.001 0.523 0.002 0.063
Total medical co-morbidities 7.3 (2.9) 5.7 (1.7) 5.9 (2.6) 0.085
mCAIDE 9.0 (4.0) 10.6 (2.8) 9.3 (3.2) 0.313
Self-reported physical health 2.5 (0.6) 2.5 (0.7) 2.7 (0.8) 0.526
Self-reported mental health 2.9 (0.4) 2.8 (0.6) 2.6 (0.7) 0.143
HADS-Anxiety 9.1 (4.3) 7.2 (3.2) 7.4 (4.6) 0.249
HADS-Depression 10.7 (2.8) 7.0 (3.6) 10.4 (5.7) 0.033 0.059 0.976 0.034
MoCA 23.0 (5.1) 19.2 (5.0) 19.8 (5.0) 0.018 0.045 0.023 0.882
AD8 3.1 (1.7) 3.1 (2.2) 3.1 (2.0) 0.998
Mini Cog 2.7 (1.2) 2.2 (1.4) 2.5 (1.2) 0.462
Animal Naming 16.5 (4.6) 13.6 (4.9) 13.7 (4.7) 0.072
Trailmaking A, s 47.6 (24.8) 81.9 (58.1) 55.1 (28.9) 0.038 0.056 0.824 0.066
mPPT 11.1 (2.8) 8.0 (3.5) 10.7 (2.6) 0.001 0.003 0.813 0.002
Mean grip strength, kg 48.4 (19.2) 54.4 (19.9) 42.9 (15.5) 0.104
Metabolic age 59.4 (17.5) 70.1 (22.7) 64.6 (21.4) 0.347
Muscle mass, kg 106.5 (24.0) 103.5 (22.8) 90.9 (15.5) 0.002 0.892 0.004 0.072
Mean arterial pressure 118.1 (19.3) 120.1 (15.4) 119.7 (16.8) 0.926
Diabetes, % 8.7 29.4 21.2 0.243
Hypertension, % 52.2 76.5 71.2 0.213

Cluster 1 composition: 14.2% White (W), 26.1% African American (AA), 46.3% Hispanic (H). Mean (SD) or %. One-way analysis of variance (ANOVA) with post-hoc Tukey honestly significant tests were used to analyze continuous variables. Chi-square tests with post-hoc Benjamini-Hochberg correction were used for categorical variables.

Bold indicates significant p-values.

SES, socioeconomic status; mCAIDE, modified Cardiovascular Risk Factors, Aging, and Incidence of Dementia; HADS, Hospital Anxiety and Depression Scale; mPPT, mini-Physical Performance Test; MoCA, Montreal Cognitive Assessment.