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. Author manuscript; available in PMC: 2023 Dec 20.
Published in final edited form as: J Alzheimers Dis. 2021;84(4):1563–1576. doi: 10.3233/JAD-215020

Table 5.

Comparison of medical history by racial/ethnic groups in cluster 2 (Younger age, Midlevel SES)

Variable White
(n = 58)
African American
(n = 23)
Hispanic
(n = 56)
ANOVA
p
Post-hoc comparison p
W versus AA W versus H H versus AA
Age, y 62.4 (7.1) 61.0 (10.4) 63.3 (9.3) 0.567
Hollingshead SES 27.0 (13.3) 36.5 (12.9) 47.6 (18.3) <0.001 0.037 <0.001 0.013
Education, y 16.3 (2.7) 14.2 (2.4) 12.8 (3.9) <0.001 0.022 <0.001 0.211
Sex, % Female 51.7 69.6 76.8 0.017 0.320 0.019 0.573
Total medical co-morbidities 3.6 (1.5) 2.6 (1.5) 2.8 (1.5) 0.004 0.022 0.010 0.904
mCAIDE 4.4 (3.9) 5.5 (3.1) 6.4 (3.6) 0.017 0.413 0.012 0.625
Self-reported physical health 1.9 (0.6) 1.7 (0.6) 1.9 (0.6) 0.526
Self-reported mental health 1.9 (0.7) 1.6 (0.6) 1.8 (0.4) 0.146
HADS-Anxiety 4.2 (2.9) 4.2 (2.8) 4.4 (3.2) 0.932
HADS-Depression 3.4 (2.5) 4.2 (2.8) 4.6 (3.5) 0.110
MoCA 24.4 (5.1) 22.0 (5.8) 22.8 (5.3) 0.114
AD8 1.3 (1.7) 0.9 (1.5) 1.2 (1.4) 0.661
Mini Cog 2.9 (1.4) 2.6 (1.3) 2.6 (1.3) 0.569
Animal Naming 20.7 (8.0) 18.1 (6.6) 17.2 (5.8) 0.058
Trailmaking A, s 46.8 (45.0) 36.7 (16.9) 47.9 (25.4) 0.470
mPPT 13.2 (2.0) 12.4 (3.5) 13.4 (1.3) 0.150
Mean grip strength, kg 66.9 (25.2) 68.0 (27.0) 57.2 (28.4) 0.214
Metabolic age 50.1 (20.5) 62.2 (23.5) 55.7 (18.8) 0.060
Muscle mass, kg 112.4 (26.5) 102.1 (24.0) 91.5 (20.2) <0.001 0.211 <0.001 0.204
Mean arterial pressure 115.4 (13.5) 116.5 (18.0) 113.0 (13.9) 0.650
Diabetes, % 6.9 4.3 8.9 0.767
Hypertension, % 17.5 34.8 25.5 0.226

Cluster 2 composition: 35.8% White (W), 35.4% African American (AA) and 38.1% Hispanic (H). Mean (SD) or %. One-way analysis of variance (ANOVA) with post-hoc Tukey honestly significant tests were used to analyze continuous variables. Chi-square tests with post-hoc Benjamini-Hochberg correction were used for categorical variables.

Bold indicates significant p-values.

SES, socioeconomic status; mCAIDE, modified Cardiovascular Risk Factors, Aging, and Incidence of Dementia; HADS, Hospital Anxiety and Depression Scale; mPPT, mini-Physical Performance Test; MoCA, Montreal Cognitive Assessment.