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. Author manuscript; available in PMC: 2023 Dec 20.
Published in final edited form as: J Alzheimers Dis. 2021;84(4):1563–1576. doi: 10.3233/JAD-215020

Table 6.

Comparison of medical history by racial/ethnic groups in cluster 3 (Older age, High SES)

Variable White
(n = 81)
African American
(n = 25)
Hispanic
(n = 23)
ANOVA
p
Post-hoc comparison p
W versus AA W versus H H versus B
Age, y 72.9 (7.7) 71.8 (8.1) 70.4 (7.5) 0.383
Hollingshead SES 23.4 (9.9) 30.8 (10.9) 30.1 (12.0) 0.002 0.008 0.021 0.976
Education, y 17.1 (2.1) 15.5 (2.1) 16.3 (2.6) 0.008 0.007 0.291 0.454
Sex, % Female 53.1 88.0 60.9 0.007 0.006 0.636 0.069
Total medical co-morbidities 7.7 (2.4) 8.4 (2.8) 7.2 (2.0) 0.196
mCAIDE 7.5 (3.7) 8.2 (3.5) 7.3 (3.1) 0.596
Self-reported physical health 1.9 (0.6) 2.2 (0.6) 2.2 (0.6) 0.026 0.064 0.114 0.988
Self-reported mental health 1.7 (0.5) 1.8 (0.4) 1.9 (0.6) 0.160
HADS-Anxiety 4.2 (2.5) 4.9 (3.0) 5.6 (3.1) 0.091
HADS-Depression 4.1 (3.2) 4.6 (3.5) 5.7 (3.2) 0.090
MoCA 25.3 (3.6) 22.2 (6.5) 23.0 (3.7) 0.004 0.008 0.077 0.817
AD8 1.3 (1.6) 1.4 (1.8) 2.0 (2.0) 0.222
Mini Cog 3.1 (1.2) 2.7 (1.3) 3.1 (1.1) 0.290
Animal Naming 18.2 (5.9) 16.5 (7.4) 17.2 (5.3) 0.591
Trailmaking A, s 34.2 (10.0) 50.1 (40.5) 42.8 (18.8) 0.026 0.024 0.326 0.554
mPPT 12.3 (2.5) 10.3 (3.4) 12.9 (1.6) 0.001 0.003 0.607 0.002
Mean grip strength, kg 58.3 (26.1) 55.3 (18.8) 56.3 (26.0) 0.899
Metabolic age 54.9 (19.8) 71.1 (17.3) 66.9 (17.5) <0.001 0.001 0.024 0.718
Muscle mass, kg 108.2 (22.8) 100.3 (15.5) 97.5 (19.6) 0.057
Mean arterial pressure 118.9 (14.4) 119.4 (14.5) 113.1 (12.9) 0.412
Diabetes, % 5.0 40.0 34.8 <0.001 <0.001 0.001 0.772
Hypertension, % 47.4 68.0 74.0 0.019 0.101 0.058 0.756

Cluster 3 Composition: 50.0% White (W), 38.5% African American (AA) and 15.6% Hispanic (H). Mean (SD) or %. One-way analysis of variance (ANOVA) with post-hoc Tukey honestly significant tests were used to analyze continuous variables. Chi-square tests with post-hoc Benjamini-Hochberg correction were used for categorical variables.

Bold indicates significant p-values.

SES, socioeconomic status; mCAIDE, modified Cardiovascular Risk Factors, Aging, and Incidence of Dementia; HADS, Hospital Anxiety and Depression Scale; mPPT, mini-Physical Performance Test; MoCA, Montreal Cognitive Assessment.