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. Author manuscript; available in PMC: 2024 Feb 1.
Published in final edited form as: Am J Psychiatry. 2023 Jun 7;180(8):584–593. doi: 10.1176/appi.ajp.21090892

FIGURE 2. Heritability and genetic correlation analyses for AUD–less stringent, AUD, AUD–AUDIT-C >0, AUDIT-C, and AUDIT-C >0a.

FIGURE 2.

aPanel A shows effect sizes from the five cross-ancestry meta-analyses. All are correlated with AUD–stringent. In panel B, heritability is calculated for European Americans and African Americans using linkage disequilibrium score regression (LDSC). Error bars indicate standard error. Panel C shows genetic correlations with other phenotypes in European Americans calculated using LDSC. Nongray bars are significant at a Bonferroni-corrected p value of 1.95×10−4. Error bars indicate 95% confidence interval. AUD=alcohol use disorder; AUDIT-C=consumption subscale of the Alcohol Use Disorders Identification Test.