Table 4. Conditions Used for Cl/18F Radiofluorination Experiments; Total Solvent Volume 1 mL in Each Case.
| precursor | mass (mg) | precursor conc. (nm) | solvent | T/°C (time/min) | % RCY |
|---|---|---|---|---|---|
| [GaCl(Bn-NODP)]·4H2O | 1 | 1424 | 75:25 (EtOH/H2O) | 80 (10) | 58 ± 5a |
| [GaCl(Bn-NODP)]·4H2O | 1 | 1424 | 45:30:25 (NaOAc/MeCN/H2O) | 80 (10) | 71 ± 15b |
| [GaCl(Bn-NODP)]·4H2O | 0.1 | 142 | 45:30:25 (NaOAc/MeCN/H2O) | 80 (10) | 6 ± 2b |
| [FeCl(Bn-NODP)]·3H2O | 1 | 1511 | 75 25 (EtOH/H2O) | 80 (10) | 83 ± 9b |
| [FeCl(Bn-NODP)]·3H2O | 0.1 | 151 | 75:25 (EtOH/H2O) | 80 (10) | 77 ± 6a |
a
N = 2.
b
N = 3.