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. 2023 Dec 6;11:1260726. doi: 10.3389/fchem.2023.1260726

TABLE 3.

Screening of the solvent in the reaction of hydroamination promoted by 2b.

Entry a Solvent Yield (%) b
1 CH3CN 70
2 1,4-Dioxane 20
3 Dimethylsulfoxide 13
4 C2H2Cl4 45
5 Toluene 50
6 Ethylene Carbonate 35
a

Reaction conditions: 1.0 mmol aniline, 1.5 mmol phenylacetylene, 1% mol 2b, 2% mol Ag salt, 90°C oil-bath, 16h, solvent (1 mL).

b

Yields are averaged from two runs and determined by 1H-NMR, analysis through internal standard.