Table 1 (abstract O-28).
Laboratory study at diagnosis
| Patient number | Plasma C1-INH function (> 50%) | Antigenic C1-INH (16.0–33.0 mg/dL) | Serum C4 levels (14.0–60.0 mg/dL) | Serum C1q levels (> 100 µg/dL) | Autoantibodies anti C1INH (antiC1INHAbs) | Immunocomplexes C1INH–antiC1INHAb | SERPING1 gene study |
|---|---|---|---|---|---|---|---|
| 1 | 50 | 4.8 | 1.67 | 60 | ND | ND | ND |
| 2 | 10.4 | 27.5 | 7.71 | 60 | ND | ND | ND |
| 3 | 11 | 9.8 | 138 | ND | ND | ND | |
| 4 | 40 | 9.89 | 2 | 58 | Negative | ND | ND |
| 5 | 18 | 2.8 | 1.4 | 11.5 | IgG | ND | ND |
| 6 | 14.06 | 17.9 | 16.4 | 120 | Negative | ND | Negative |
| 7 | 25.67 | 16.2 | 157.95 | IgG | ND | Negative | |
| 8 | 6 | 15 | 1.56 | 0 | IgA | Negative | Negative |
| 9 | 10.77 | 5.82 | 1.56 | 0 | IgA, IgG | ND | Negative |
| 10 | 21.61 | 13 | 35.9 | 233.16 | Negative* | Negative* | Negative |
| 11 | 33.46 | 12.1 | 1.66 | 32.13 | Negative | IgG | Negative |
| 12 | 19.64 | 4.62 | 5.32 | 111.88 | IgA, IgM | Negative | Negative |
| 13 | 25.96 | 3.99 | 1.5 | 71.82 | Negative | IgA, IgG | Negative |
| 14 | 11.38 | 5.49 | 3.53 | 58.11 | IgM | Negative | Negative |
| 15 | 7.9 | 5.24 | ND | 115.58 | IgG | Negative | Negative |
ND: Not done.
*Patient 10 had positive autoC1-INHabs several years later.