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. 2023 Dec 19;23:1021. doi: 10.1186/s12903-023-03760-y

Table 1b.

Selected species potentially related to the progression in the development of oral cancer

Species Degrees of epithelial dysplasia p-value Groups p-value
HK ED OSCC HC OLK OSCC
S. sp. NPS 308 0.04% 0.22% 0.43% 0.024 0.09% 0.12% 0.43% 0.029
S. agalactiae 0.06% 0.12% 0.23% 0.009 0.06% 0.08% 0.23% 0.001
G. morbillorum 0.06% 0.22% 1.20% 0.002 0.16% 0.13% 1.20% 0.001
G. haemolysans 0.27% 0.41% 0.91% 0.007 0.20% 0.33% 0.91% < 0.001

HK, hyperplasia/keratosis; ED, epithelial dysplasia; HC, healthy controls; OLK, oral leukoplasia; OSCC, oral squamous cell carcinoma; S. sp. NPS 308, Streptococcus sp. NPS 308; S. agalactiae, Streptococcus agalactiae; G. morbillorum, Gemella morbillorum; G. haemolysans, Gemella haemolysans