Table 2.
Characteristics of participants
| Variable | n=2053 |
|---|---|
| Time from onset to randomization, min | 57 (38–83) |
| Time from onset to ambulance call, min | 23 (10–47) |
| Time from onset to ambulance arrival, min | 42 (25–69) |
| Age, years | 70 (13) |
| Female | 781/2017 (39) |
| Systolic BP, mmHg | 178 (21) |
| Diastolic BP, mmHg | 98 (16) |
| Heart rate, bpm | 83 (16) |
| FAST score on assessment1 | 3 (2–4) |
| Glucose, mmol/L | 7.3 (6.3–9.0) |
| NIHSS score at hospital arrival2 | 12 (6–18) |
| GCS score at hospital arrival3 | 13 (10–15) |
| Hypertension | 1265/1777 (71.2) |
| Currently treated hypertension | 887/1775 (50.0) |
| Coronary artery disease | 210/1777 (11.8) |
| Other heart disease | 99/1777 (5.6) |
| Atrial fibrillation | 148/1777 (8.3) |
| Diabetes mellitus | 302/1777 (17.0) |
| Hypercholesterolemia | 30/1776 (1.7) |
| Current smoker | 308/1773 (17.4) |
| Pre-stroke independent function (mRS score 0) | 1140/1774 (64.3) |
| Anticoagulant use | 47/1773 (2.7) |
| Aspirin/other antiplatelet agent | 156/1771 (8.8) |
| Statin/other lipid lowering treatment | 123/1770 (6.9) |
| Presumed pathology by day 74 | |
| Intracerebral hemorrhage | 754/1676 (44.9) |
| Ischemic stroke | 836/1676 (50.0) |
| Non-stroke | 86/1676 (5.1) |
Data are n/N (%), mean (SD), or median (IQR)
FAST Face, Arm, Speech, and Time scale, GCS Glasgow coma scale, mRS modified Rankin scale, NIHSS National Institutes of Health Stroke Scale, BP blood pressure
1Scores range from 0 to 4, 1 score for each Face/Arm/Speech/Time deficit
2Scores range from 0 to 42, with higher scores indicating greater neurological deficit
3Scores range from 15 (normal) to 3 (deep coma)
4Diagnosis according to the clinician’s interpretation of clinical features and results of brain imaging at the time of admission