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. 2023 Dec 19;22:262. doi: 10.1186/s12934-023-02266-0

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 8 — Impact of the carbon source on growth and pamamycin production in S. lividans ΔYA8-R2. The recombinant strain was grown in minimal medium containing either 30 mM mannitol (A) or 30 mM 4-hydroxybenzoate (4HB) (B). In addition, the spectrum of pamamycins formed is given for the mid-exponential (72 h) and stationary phases (216 h) on mannitol (C) and 4HB (D). The data represent mean values and standard deviations from three biological replicates (n = 3)