Table 3.

Subgroup analyses for prediction of ESKD at 3 years

Subgroup	AUROC
	LASSO regression	Random forest	XGBoost	Neural network
eGFR
15–20 mL/min/1.73m2 (n = 413)	0.69 (0.63 to 0.74)	0.69 (0.64 to 0.75)	0.65 (0.63 to 0.74)	0.70 (0.65 to 0.75)
20–29 mL/min/1.7m2 (n = 1,747)	0.74 (0.72 to 0.77)	0.74 (0.71 to 0.76)	0.73 (0.71 to 0.76)	0.75 (0.72 to 0.77)
Sex
Female (n = 1,695)	0.79 (0.76 to 0.82)	0.78 (0.75 to 0.81)	0.77 (0.74 to 0.81)	0.79 (0.76 to 0.82)
Male (n = 1,465)	0.75 (0.71 to 0.78)	0.74 (0.71 to 0.77)	0.74 (0.71 to 0.78)	0.75 (0.72 to 0.78)
Race
Black (n = 401)	0.74 (0.68 to 0.80)	0.75 (0.69 to 0.81)	0.75 (0.66 to 0.79)	0.74 (0.68 to 0.80)
Hispanic (n = 320)	0.73 (0.66 to 0.80)	0.71 (0.64 to 0.79)	0.71 (0.65 to 0.79)	0.73 (0.66 to 0.80)
White (n = 1,211)	0.77 (0.73 to 0.81)	0.78 (0.74 to 0.81)	0.78 (0.72 to 0.81)	0.77 (0.73 to 0.81)
Others (n = 1,228)	0.78 (0.74 to 0.81)	0.76 (0.73 to 0.80)	0.76 (0.74 to 0.81)	0.78 (0.75 to 0.81)
Comorbidity
BMI ≥ 25 kg/m2 (n = 1,424)	0.78 (0.75 to 0.80)	0.78 (0.75 to 0.80)	0.77 (0.75 to 0.80)	0.78 (0.76 to 0.81)
Diabetes (n = 1,522)	0.76 (0.73 to 0.79)	0.71 (0.73 to 0.79)	0.76 (0.72 to 0.79)	0.76 (0.72 to 0.79)
Cardiovascular disease	0.75	0.77	0.76	0.77
(n = 1,447)	(0.72 to 0.79)	(0.73 to 0.80)	(0.72 to 0.79)	(0.73 to 0.80)
Laboratory value
K > 5.5 mEq/L	0.82	0.82	0.80	0.82
(n = 282)	(0.75 to 0.89)	(0.75 to 0.89)	(0.74 to 0.88)	(0.75 to 0.89)
Phosphate > 5 mg/dL	0.73	0.71	0.68	0.73
(n = 114)	(0.64 to 0.81)	(0.61 to 0.80)	(0.62 to 0.80)	(0.64 to 0.82)
Serum albumin < 3.0	0.80	0.79	0.78	0.78
(n = 110)	(0.73 to 0.86)	(0.72 to 0.86)	(0.70 to 0.85)	(0.71 to 0.85)