Fig. 7: Effects of NFEPP on human colonic nociceptors.
A. Representative traces and histograms of colonic afferent nerve firing in response to von Frey filament probing (10 g) at pH 7.4 (control), pH 6.5 (control), in presence of NFEPP (300 nM) at pH 6.5 and after washout at pH 7.4. B-C. Summary bar charts of afferent nerve probing responses (N=3) presented as Hz (B) and as % of control at pH 7.4 (C). Abbreviations: Hz, Hertz. * p<0.05. Friedman test, Dunńs test.