Table 3.
The association between the EAT-Lancet reference diet score and incident major cardiovascular events
| Incident major cardiovascular events |
Stroke |
Ischemic stroke |
Hemorrhagic stroke |
Myocardial infarction |
||||||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| HR (95% CI) | HR (95% CI) | HR (95% CI) | HR (95% CI) | HR (95% CI) | ||||||||||||||||
| EAT-Lancet reference diet score | Number of casesa | Model 1 b | Model 2 c | Model 3c d | Number of casesa | Model 1 b | Model 2 c | Model 3c d | Number of casesa | Model 1 b | Model 2 c | Model 3c d | Number of casesa | Model 1 b | Model 2 c | Model 3c d | Number of casesa | Model 1 b | Model 2 c | Model 3c d |
| Continuous, 0-11 | 7,530 | 0.99 (0.98–1.01) | 1.00 (0.98–1.01) | 0.97 (0.96–0.98) | 2,901 | 0.99 (0.97–1.01) | 0.99 (0.97–1.02) | 0.99 (0.97–1.02) | 2,049 | 0.99 (0.96–1.02) | 1.00 (0.97–1.03) | 1.00 (0.97–1.03) | 414 | 1.02 (0.95–1.08) | 1.02 (0.95–1.08) | 1.02 (0.95–1.08) | 4,670 | 0.99 (0.97–1.01) | 1.00 (0.99–1.02) | 1.00 (0.98–1.02) |
| Low adherence, 0-4 | 3,794 | Ref. | Ref. | Ref. | 1,430 | Ref. | Ref. | Ref. | 1,000 | Ref. | Ref. | Ref. | 198 | Ref. | Ref. | Ref. | 2,384 | Ref. | Ref. | Ref. |
| Moderate adherence, 5-7 | 3,383 | 0.97 (0.93–1.02) | 0.98 (0.94–1.03) | 0.92 (0.88–0.97) | 1,336 | 0.99 (0.92–1.07) | 1.00 (0.93–1.08) | 1.00 (0.93–1.08) | 954 | 1.01 (0.93–1.11) | 1.02 (0.94–1.12) | 1.02 (0.94–1.12) | 194 | 1.03 (0.84–1.26) | 1.04 (0.85–1.27) | 1.04 (0.85–1.27) | 2,067 | 0.96 (0.90–1.02) | 0.97 (0.91–1.03) | 0.97 (0.91–1.02) |
| High adherence, 8-11 | 353 | 1.07 (0.96–1.19) | 1.09 (0.98–1.21) | 0.94 (0.84–1.05) | 135 | 1.02 (0.85–1.22) | 1.04 (0.87–1.24) | 1.03 (0.87–1.23) | 95 | 1.02 (0.83–1.27) | 1.04 (0.84–1.29) | 1.04 (0.84–1.28) | 22 | 1.17 (0.75–1.82) | 1.18 (0.76–1.84) | 1.18 (0.76–1.83) | 219 | 1.10 (0.95–1.26) | 1.12 (0.98–1.29) | 1.11 (0.97–1.28) |
Abbreviations: CI: confidence interval; HR: hazard ratio.
A small number of participants was diagnosed with both stroke and myocardial infraction on the same day, thus the number of cases of the individual major cardiovascular events does not add up to the total. Similarly, a small number of participants was diagnosed with both main stroke subtypes on the same day.
Model based on age, sex, and region.
Model based on age, sex, and region plus further adjustment for smoking status, body mass index, physical activity, highest level of attained education, Townsend deprivation index and alcohol intake status.
Model based on age, sex, region, smoking status, body mass index, physical activity, highest level of attained education, Townsend deprivation index and alcohol intake status (Model 2), further adjusted for first-degree family history for heart disease and stroke.