Table 3.
Recording of Breast Cancer Diagnosis, Treatments, and Supporting Clinical Codes During Follow-Up in CPRD Aurum and CPRD GOLD
| Breast Cancer Data Elementa | CPRD AurumN=131,936 (%) | CPRD GOLDN=69,102 (%) |
|---|---|---|
| Breast cancer diagnosis | 120,084 (91.0) | 62,877 (91.0) |
| Mean number codes ± st. dev. | 5.8 ± 11.9 | 1.3 ± 1.0 |
| Median (IQR) | 2 (1–5) | 1 (1–1) |
| Mastectomy | 38,459 (29.2) | 19,853 (28.7) |
| Mean number codes ± st. dev. | 1.6 ± 2.2 | 1.1 ± 0.4 |
| Median (IQR) | 1 (1–2) | 1 (1–1) |
| Lumpectomy | 43,581 (33.0) | 20,001 (28.9) |
| Mean number codes ± st. dev. | 1.4 ± 1.7 | 1.1 ± 0.4 |
| Median (IQR) | 1 (1–1) | 1 (1–1) |
| Breast cancer drug prescription | 97,130 (73.6) | 51,272 (74.2) |
| Mean number codes ± st. dev. | 39.6 ± 35.7 | 31.9 ± 28.8 |
| Median (IQR) | 32 (17–55) | 26 (11–44) |
| Radiation | 26,044 (19.7) | 7967 (11.5) |
| Mean number codes ± st. dev. | 1.3 ± 0.7 | 1.1 ± 0.4 |
| Median (IQR) | 1 (1–1) | 1 (1–1) |
| Chemotherapy | 18,496 (14.0) | 9301 (13.5) |
| Mean number codes ± st. dev. | 2.2 ± 2.9 | 1.8 ± 2.0 |
| Median (IQR) | 1 (1–2) | 1 (1–2) |
| Suspected breast cancer | 24,800 (18.8) | 4201 (6.1) |
| Mean number codes ± st. dev. | 1.3 ± 1.3 | 1.1 ± 0.3 |
| Median (IQR) | 1 (1–1) | 1 (1–1) |
| Lump symptom | 58,434 (44.3) | 30,799 (44.6) |
| Mean number codes ± st. dev. | 1.6 ± 2.2 | 1.4 ± 0.9 |
| Median (IQR) | 1 (1–2) | 1 (1–2) |
| Breast cancer biopsy | 17,117 (13.0) | 8913 (12.9) |
| Mean number codes ± st. dev. | 1.2 ± 0.9 | 1.1 ± 0.4 |
| Median (IQR) | 1 (1–1) | 1 (1–1) |
| Cancer care | 109,088 (82.7) | 54,670 (79.1) |
| Mean number codes ± st. dev. | 2.1 ± 2.8 | 2.1 ± 2.9 |
| Median (IQR) | 1 (1–2) | 1 (1–2) |
| Referral or visit to specialist | 107,368 (81.4) | 47,410 (68.6) |
| Mean number codes ± st. dev. | 9.7 ± 9.5 | 9.1 ± 8.8 |
| Median (IQR) | 7 (3–13) | 7 (3–12) |
| Palliative care | 14,791 (11.2) | 6876 (10.0) |
| Mean number codes ± st. dev. | 3.7 ± 5.7 | 3.2 ± 4.6 |
| Median (IQR) | 2 (1–4) | 1 (1–3) |
Note: aNumber of codes restricted to 1 per date among patients with at least one code.
Abbreviations: IQR, Interquartile range; st.dev, Standard Deviation.