TABLE 2.
Patient treatment, immune response, disease status, PFS, and OS (ordered by clinical response/PFS)
| Patient ID | Age | ECOG | Prior therapies for recurrent disease | Vaccine doses | Immune response | Clinical best response | PFS (months) | OS (months) |
|---|---|---|---|---|---|---|---|---|
| UPN017 | 71 | 0 | 2 | 3 | R | PR | 32.5+ | 32.5+ |
| UPN012 | 54 | 1 | 2 | 3 | R | PR | 15.2 | 28.0+ |
| UPN018 | 55 | 0 | 3 | 3 | R | PR | 10.2 | 19.4+ |
| UPN020 | 69 | 0 | 3 | 1 | N/A | SD | 27.8+ | 27.8+ |
| UPN008 | 70 | 0 | 3 | 3 | R | SD | 6.6 | 35.8+ |
| UPN013 | 64 | 1 | 3 | 3 | R | SD | 6.0 | 14.6 |
| UPN019 | 70 | 0 | 2 | 1 | N/A | SD | 5.5 | 18.6+ |
| UPN009 | 74 | 1 | 2 | 3 | R | SD | 3.9+ | 30.4 |
| UPN005 | 64 | 0 | 2 | 3 | NR | SD | 3.8 | 19.7 |
| UPN023 | 79 | 1 | 4 | 1 | N/A | N/A | 0.7+ | 9.4 |
| UPN003 | 63 | 0 | 1 | 2 | N/A | PD | 2.4 | 25.9 |
| UPN007 | 53 | 1 | 3 | 3 | N/A | PD | 2.1 | 3.8 |
| UPN010 | 55 | 1 | 4 | 3 | NR | PD | 2.0 | 6.1 |
| UPN028 | 67 | 0 | 3 | 3 | NR | PD | 2.0 | 5.3+ |
| UPN001 | 64 | 1 | 1 | 3 | NR | PD | 1.8 | 45.5+ |
| UPN026 | 57 | 1 | 3 | 3 | NR | PD | 1.8 | 5.0 |
| UPN016 | 47 | 1 | 1 | 3 | NR | PD | 1.8 | 20.5 |
| UPN015 | 66 | 0 | 2 | 3 | NR | PD | 1.8 | 32.6 |
| UPN021 | 57 | 1 | 4 | 3 | NR | PD | 1.8 | 4.4 |
| UPN025 | 56 | 0 | 2 | 3 | NR | PD | 1.8 | 15.1 |
| UPN022 | 54 | 0 | 2 | 3 | NR | PD | 1.7 | 4.8 |
| UPN027 | 62 | 1 | 1 | 3 | NR | PD | 1.7 | 13.0 |
| UPN014 | 68 | 1 | 1 | 2 | N/A | PD | 1.6 | 10.4 |
| UPN006 | 43 | 0 | 2 | 2 | N/A | PD | 1.6 | 5.8 |
| UPN024 | 72 | 1 | 4 | 3 | NR | PD | 1.6 | 4.6 |
| UPN002 | 68 | 0 | 3 | 2 | N/A | PD | 1.5 | 2.5 |
| UPN011 | 63 | 1 | 2 | 2 | N/A | PD | 1.4 | 13.3 |
| UPN004 | 68 | 1 | 1 | 1 | N/A | PD | 0.7 | 20.9+ |
Abbreviations: +: censored, N/A: not assessed/not available, NR: immune non-responder, PD: progressive disease, PR: partial response, R: immune responder; SD: stable disease, TE: too early (no CT scans).