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. 2023 Dec 15;62(1):33–41. doi: 10.1080/13880209.2023.2292266

Figure 3.

Figure 3.

SFI inhibits the STAT3/AKT branch activated by IL-22 treatment in PC9/GR and H1975 cells. (A, B) Western blot of PC9/GR and H1975 cells determining p-STAT3 and p-AKT following stimulation with IL-22 (50 ng/mL) for 10 or 30 min. (C, D) Western blot analysis of PC9/GR and H1975 cells was stimulated with IL-22 (50 ng/mL) for 20 min after pre-treated or not with 10 mg/mL SFI for 24 h or 48 h. Results are expressed as mean ± SEM (n = 3) *p < 0.05, **p < 0.01, ***p < 0.001 when compared with control group; #p < 0.05, ##p < 0.01, ###p < 0.001 when compared with IL-22 group in A, B, C, and D.