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. 2023 Dec 6;11(50):17870–17880. doi: 10.1021/acssuschemeng.3c07024

Table 2. Yields and Reaction Mass Efficiency (RME) for the Alkylation Reaction of the N-Lactamides.

ammonium salt yield (%)a RME (%)
[N112-Lac-4]I 92 72
[N113-Lac-4]I 95 75
[N113-Lac-6]I 97 76
[N113-Lac-8]I 98 76
[N113-Lac-10]I 83 63
[N113-Lac-12]I 93 70
[N112-Lac-12]I 92 69
[Im3-Lac-4]I 99 74
[Im3-Lac-12]I 97 79
     
[N113-Lac-4]Br 91 74
[N113-Lac-12]Br 70 53
a

Yields were reproducible within ±2.0%.