Table 2.
Univariate and multivariate logistic analyses of risk factors associated with a poor prognosis
| Univariate analysis |
Multivariate analysis |
|||||
|---|---|---|---|---|---|---|
| OR | 95% CI | P-value | OR | 95% CI | P-value | |
| Age, years | 1.56 | 0.89–2.73 | 0.13 | - | - | - |
| Male | 0.69 | 0.42–1.11 | 0.12 | - | - | - |
| MBP, mmHg | 0.60 | 0.31–1.14 | 0.13 | - | - | - |
| Laboratory parameters | ||||||
| PH | 0.98 | 0.70–1.36 | 0.89 | - | - | - |
| Na+, mmol/L | 0.75 | 0.48–1.18 | 0.21 | - | - | - |
| K+, mmol/L | 0.64 | 0.37–1.10 | 0.11 | - | - | - |
| Lactic acid, mmol/L | 1.84 | 1.13–3.00 | 0.01 | 1.83 | 1.08–3.09 | 0.02 |
| Serum glucose, mmol/L | 1.24 | 0.76–2.02 | 0.40 | - | - | - |
| Leukocyte, ×109/L | 0.83 | 0.49–1.39 | 0.48 | - | - | - |
| Platelets, ×109/L | 0.49 | 0.26–0.91 | 0.15 | - | - | - |
| HCT, % | 1.36 | 0.84–2.20 | 0.21 | - | - | - |
| TBil, mg/dL | 1.79 | 1.05–3.07 | 0.04 | 2.01 | 1.11–3.63 | 0.02 |
| Crea, μmol/L | 1.39 | 0.83–2.34 | 0.21 | - | - | - |
| Urea, mmol/L | 1.36 | 0.84–2.19 | 0.21 | - | - | - |
| ALB, g/L | 0.98 | 0.56–1.70 | 0.93 | - | - | - |
| I-Ammonia, μmol/L | 1.80 | 1.16–2.80 | 0.01 | - | - | - |
| H-Ammonia, μmol/L | 1.84 | 1.22–2.79 | <0.001 | - | - | - |
| M-Ammonia, μmol/L | 1.99 | 1.24–3.18 | <0.001 | 1.73 | 1.07–2.80 | 0.02 |
| Score system | ||||||
| APACHE-II | 4.22 | 2.50–7.12 | <0.001 | 3.08 | 1.63–5.80 | <0.001 |
| GCS | 0.31 | 0.18–0.52 | <0.001 | 0.52 | 0.28–1.00 | 0.05 |
| SOFA | 2.47 | 1.72–5.52 | 0.01 | 2.01 | 1.93–4.59 | 0.02 |
Data were expressed as OR (95% CI). P < 0.05 was considered statistically significant. H-, M-, and I- separately means the highest level, the mean level, and the initial level; ALB: albumin; APACHE-II: Acute Physiologic Assessment and Chronic Health Evaluation II; CI: confidence interval; Crea: creatinine; GCS: Glasgow Coma Scale; NHH: non-hepatic hyperammonemia; HCT: hematocrit; MBP: mean blood pressure; OR: odds ratio; SOFA: Sequential Organ Failure Assessment; TBil: total bilirubin.