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. 2023 Dec 20;18(12):e0295919. doi: 10.1371/journal.pone.0295919

Table 4. Association between body mass index trajectories and cause-specific mortality hazard ratioa.

Male aged over 60 low-normal weight, stable Mid-normal weight, stable Overweight, stable Obesity, stable
Cancer 1.06 (0.90, 1.25) 1 1.01 (0.89, 1.13) 1.336*** (1.09, 1.64)
Cardiovascular disease 0.94 (0.77, 1.15) 1 0.994 (0.87, 1.14) 1.336*** (1.06, 1.69)
Respiratory disease 1.70*** (1.39, 2.08) 1 0.817** (0.68, 0.98) 1.027 (0.73, 1.46)
Others 1.33** (1.14, 1.55) 1 1.004 (0.89, 1.13) 1.232 (0.99, 1.53)
Male aged 40–60 low-normal weight, increasing Mid-normal weight, increasing Overweight, increasing Obesity, increasing
Cancer 1.02 (0.92, 1.30) 1 1.061 (0.95, 1.18) 1.205 (0.99, 1.46)
Cardiovascular disease 1.12 (0.90, 1.40) 1 1.363** (1.16, 1.61) 2.079*** (1.61, 2.68)
Respiratory disease 1.85*** (1.31, 2.61) 1 1.002 (0.71, 1.41) 0.699 (0.32, 1.51)
Others 1.25** (1.07, 1.46) 1 1.07 (0.94, 1.22) 1.425** (1.15, 1.77)
Female aged over 60 low-normal weight, increasing Mid-normal weight, increasing Overweight, increasing Obesity, increasing
Cancer 0.92 (0.75, 1.12) 1 1.01 (0.86, 1.19) 0.75*** (0.60, 0.93)
Cardiovascular disease 1.08 (0.89, 1.31) 1 1.10 (0.96, 1.22) 1.35* (1.02, 1.81)
Respiratory disease 1.94*** (1.45, 2.58) 1 1.19 (0.94, 1.21) 1.24 (0.70, 2.22)
Others 1.21* (1.04, 1.40) 1 1.10 (0.95, 1.26) 1.56** (1.24, 1.96)
Female aged 40–60 low-normal weight, increasing Mid-normal weight, increasing Overweight, increasing Obesity, increasing
Cancer 0.96 (0.84, 1.09) 1 1.04 (0.91, 1.18) 1.02 (0.79, 1.32)
Cardiovascular disease 1.15 (0.90, 1.48) 1 1.50** (1.19, 1.88) 1.62* (1.09, 2.41)
Respiratory disease 1.74*** (1.10, 2.74) 1 1.11 (0.68, 1.82) 2.03 (0.98, 4.19)
Others 1.09 (0.92, 1.30) 1 1.23* (1.04, 1.45) 1.68** (1.29, 2.19)

a: Fully adjusted model: Adjusted for age, education level, smoking status, alcohol consumption and physical activity.

*p<0.05,

**p<0.01,

***p<0.0001.