Table 2. Association between dietary omega-3 intake and CHD in different models.

Variable	N	Crude OR (95%CI)	P-value	Model 1 OR (95%CI)	P-value	Model 2 OR (95%CI)	P-value	Model 3 OR (95%CI)	P-value
Omega-3 (g/d)
Q1 (≤ 1.00)	6,285	1(Ref)		1(Ref)		1(Ref)		1(Ref)
Q2 (1.01–1.41)	6,223	0.90 (0.75, 1.09)	0.293	0.91 (0.74, 1.11)	0.345	0.91 (0.74, 1.14)	0.424	0.90 (0.72, 1.12)	0.356
Q3 (1.42–1.87)	6,266	0.86 (0.70, 1.07)	0.171	0.92 (0.74, 1.14)	0.442	0.93 (0.75, 1.17)	0.552	0.91 (0.73, 1.14)	0.404
Q4 (1.88–2.57)	6,195	0.75 (0.60, 0.92)	0.007	0.78 (0.62, 0.97)	0.028	0.78 (0.62, 0.99)	0.044	0.80 (0.63, 1.01)	0.065
Q5 (≥ 2.58)	6,215	0.74 (0.60, 0.91)	0.005	0.76 (0.61, 0.95)	0.018	0.79 (0.63, 1.00)	0.049	0.76 (0.60, 0.96)	0.022
Trend p		0.006		0.022		0.054		0.032

Abbreviations: Q1 to Q5, quintile 1 to 5; OR, odds ratio; CI, confidence interval; Ref, reference.

Crude: unadjusted.

Model 1: adjusted for age + sex + race/ethnicity + education + marital status + PIR.

Model 2: adjusted for model 1 + smoking + alcohol intake + stroke + hypertension + hyperlipidemia + diabetes.

Model 3: adjusted for model 2 + dietary supplements + BMI + HDL-C + TC.