Figure 7.

Interactions and relevant pathways of GOLT1B-related genes. (A) Network of genes for targeting genes from STRING. (B) Bubble chart of KEGG pathway analysis for targeting genes from STRING and GEPIA2. (C) The cnetplot for the molecular function data in GO analysis. (D) Intersection genes of 50 GOLT1B-binding and interacted genes and top 100 GOLT1B-correlated genes from GEPIA2. (E) Genetic alteration frequency of six relevant genes in GOLT1B mutation alteration tumor groups of TCGA tumor. (F) Analysis of the expression correlation between GOLT1B and intersection genes in TCGA cancers of GEPIA2. (G) Survival maps of comparing high and low expression of relevant genes among different cancer types in GEPIA2. OS: overall survival; DFS: disease-free survival; ACC: adrenocortical carcinoma; BLCA: bladder urothelial carcinoma; BRCA: breast invasive carcinoma, CESC: cervical squamous cell carcinoma and endocervical adenocarcinoma; CHOL: cholangiocarcinoma; COAD: colon adenocarcinoma, DLBC: lymphoid neoplasm diffuse large B-cell lymphoma; ESCA: esophageal carcinoma; GBM: glioblastoma multiforme; HNSC: head and neck squamous cell carcinoma; KICH: kidney chromophobe; KIRC: kidney renal clear cell carcinoma; KIRP: kidney renal papillary cell carcinoma; LAML: acute myeloid leukemia; LGG: brain lower grade glioma; LIHC: liver hepatocellular carcinoma; LUAD: lung adenocarcinoma; LUSC: lung squamous cell carcinoma; MESO: mesothelioma; OV: ovarian serous cystadenocarcinoma; PAAD: pancreatic adenocarcinoma; PCPG: pheochromocytoma and paraganglioma; PRAD: prostate adenocarcinoma; READ: rectum adenocarcinoma; SARC: sarcoma; SKCM: skin cutaneous melanoma; STAD: stomach adenocarcinoma; TGCT: testicular germ cell tumors; THCA: thyroid carcinoma; THYM: thymoma; UCEC: uterine corpus endometrial carcinoma; UCS: uterine carcinosarcoma; UVM: uveal melanoma; KEGG: Kyoto encyclopedia of genes and genomes; GOLT1B: golgi transport 1B.