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. Author manuscript; available in PMC: 2024 Apr 13.
Published in final edited form as: Nat Rev Methods Primers. 2023 Apr 13;3:30. doi: 10.1038/s43586-023-00211-4

Fig. 5 |. Superparamagnetic iron oxide nanoparticles labelled with 69Ge for lymph node mapping via positron emission tomography and MRI.

Fig. 5 |

a, Schematic illustration of chelator-free synthesis of 69Ge-iron oxide nanoparticles (IONPs). b, Micrograph of IONPs from transmission electron microscopy. c, Lymph node (white arrow) imaging with positron emission tomography after injection of 69Ge-IONPs into left paw (red arrow) of a mouse. d, Lymph node (green circle) mapping with MRI before and after injection of 69Ge-IONPs into left paw of a mouse. Contralateral lymph node is indicated by red circle. %ID g−1, percentage of injected dose per gram of tissue; PEG, polyethylene glycol. Reprinted with permission from ref. 188, Wiley.