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. 2023 Dec 18;19(3):2288389. doi: 10.1080/21645515.2023.2288389

Table 1.

Bactericidal titers by vaccination status.

MenW isolate MenACWY vaccine
4CMenB vaccine
Adolescents
Adolescents
Infants
Pre-immune Post-immune Pre-immune Post-2nd dose Control sera Post-4th dose
ARG-2991 <16 256 <4 <4 <2 <2
ARG-3006 <16 >512 <4 >128* <2 >64
ARG-3052 <16 256 <4 >128 2 >64†
ARG-3064 <16 256 <4 >128 <2 >64
ARG-3158 <16 >512 <4 64* <2 >64
ARG-3200 <16 256 <4 >128 <2 >64
ARG-3216 <16 256 <4 >128 <2 >64*
ARG-3223 <16 256 4 >128 2 >64
ARG-3273 <16 >512 <4 >128* <2 >64*
ARG-3279 <16 ≥512 <4 64 <2 >64
ARG-3320 <16 ≥512 <4 >128* <2 >64

*Prozone effect: bacterial survival was observed at high antibody concentrations due to the prozone effect, which is often detected when there is an excess of antibodies.

Bacteriostatic.

4CMenB, 4-component meningococcal serogroup B vaccine; ARG, Argentina; MenACWY, meningococcal serogroups A, C, W, and Y; MenW, meningococcal serogroup W.