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. 2023 Dec 13;21(1):1–12. doi: 10.1080/15476286.2023.2293339

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© 2023 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The terms on which this article has been published allow the posting of the Accepted Manuscript in a repository by the author(s) or with their consent.

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Figure 2. — Sequence features of mRNAs. A-B) GC-content averaged over each exon (yellow) and intron (white) of all human protein-coding genes with 5 exons plotted from 5’ to 3’ ends. Note that in (A) each exon and intron metaplot was normalized, while in (B) they were adjusted to reflect the average length of each exon and intron of all genes in the dataset. C) Similar to (A) except that the average nucleotide-content of the coding strand was plotted from 5’ to 3’ ends.