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Sensitivity, specificity, and positive and negative predictive values of the machine learning algorithm in the ADAMANT population.
| CSF amyloid-β1-42 (A+) | CSF pTau pT181 (T+) | Combined (A+T+) | |
|---|---|---|---|
| Sensitivity | 95.5% | 78.1% | 78.1% |
| Specificity | 50.0%a | 92.9% | 92.9% |
| PPV | 97.7% | 96.2% | 96.2% |
| NPV | 50.0% | 65.0% | 65.0% |
One out of two A− patients was labelled as A+ by the algorithm.
