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. 2023 Nov 22;624(7992):682–688. doi: 10.1038/s41586-023-06746-6

Fig. 4. Molecular mechanism of group II RNP branching and exon ligation.

Fig. 4

a, Organization of catalytic elements before branching. The bpA is juxtaposed to the 5′SS and poised for lariat formation. b, Zoomed in view of (a). c, Active site configuration before exon ligation. The 5′SS is primed for attack to ligate the exons. d, Zoomed in view of (c). e, Positioning of active site elements immediately after exon ligation. f, Zoomed in view of (e). Divalent metal ions are shown as green spheres.