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. 2023 Oct 2;4(12):1648–1659. doi: 10.1038/s43018-023-00645-5

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Extended Data Fig. 10 — Kaplan-Meier plots for event-free survival stratified by ex vivo drug response to cladribine, fludarabine, vincristine and daunorubicin + cytarabine and faceted by ELN-22 risk groups. Patient groups of ex vivo responders and weak responders were defined by ex vivo drug responses dichotomized using maximally selected log rank statistics to visualize effects. Absolute numbers per groups are shown in tables below the plots. P-values are from two-sided Wald tests on Cox regression models using drug responses as continuous variables.

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