Table 1.
Participant Characteristics in the Cell Senescence/SASP Biomarker Ancillary to VEGGIE
| Baseline | |||
|---|---|---|---|
| Overall | CR | Control | |
| Characteristics (N) | 58 | 31 | 27 |
| Women | 43 | 23 | 20 |
| Men | 15 | 8 | 7 |
| Race | |||
| Black/African American | 20 | 14 | 6 |
| White | 35 | 15 | 20 |
| Other | 3 | 2 | 1 |
| Mean ± SD | Mean ± SD | Mean ± SD | |
|---|---|---|---|
| Age (yr) | 57.6 ± 5.8 | 57.4 ± 6.2 | 57.7 ± 5.3 |
| BMI (kg/m2) | 37.0 ± 5.2 | 36.1 ± 5.3 | 37.9 ± 5.9 |
| Body weight (kg) | 103 ± 14 | 100.9 ± 15.4 | 105.6 ± 11.2 |
| Waist circumference (cm) | 111.9 ± 10.5 | 110.4 ± 12.1 | 113.5 ± 7.9 |
| Fasting insulin (mIU/L) | 18.1 ± 11 | 14.6 ± 7.0 | 21.9 ± 13.3 |
| Hemoglobin A1c (HbA1c, %) | 5.75 ± 0.35 | 5.74 ± 0.41 | 5.75 ± 0.26 |
| Insulin Resistance Index (HOMA-IR) | 4.91 ± 3.06 | 4.02 ± 2.17 | 5.88 ± 3.59 |
| Fasting glucose (mg/dL) | 103.4 ± 8.3 | 102.7 ± 7.9 | 104.0 ± 7.9 |
| Creatinine (mg/dL) | 0.86 ± 0.18 | 0.86 ± 0.19 | 0.86 ± 0.16 |
| LDL cholesterol (mg/dL) | 113.2 ± 29.2 | 114.7 ± 28.4 | 111.4 ± 30.6 |
| Total cholesterol (mg/dL) | 187.8 ± 35.8 | 189.7 ± 37.1 | 185.8 ± 34.9 |
| Systolic blood pressure (mmHg) | 129.9 ± 18.5 | 131.9 ± 18.9 | 127.7 ± 18.0 |
| Diastolic blood pressure (mmHg) | 73.8 ± 8.5 | 75.4 ± 7.5 | 72.0 ± 9.3 |
Notes: BMI = body mass index; CR = Caloric restriction; HbA1c = hemoglobin A1c; HOMA = Homeostatic Model Assessment; SASP = senescence-associated secretory phenotype; SD = standard deviation.