TABLE 2.
Recovery of L. monocytogenes 10403S and the isogenic sigB mutant from tissues of infected mice after intragastric or intraperitoneal infection
| Type of inoculation and tissue | Log10 no. of bacteria/g of tissue (± SD) at the following day postinfectiona:
|
|||
|---|---|---|---|---|
| 2
|
4
|
|||
| 10403S | sigB mutant | 10403S | sigB mutant | |
| Intragastric | ||||
| Liver | 3.7 (1.2) | 3.4 (1.3) | 3.7 (0.5)c | 2.9 (0.4)c |
| Spleen | 4.0 (1.0) | 4.1 (1.5) | 4.9 (0.4) | 4.5 (0.2) |
| Intraperitoneal | ||||
| Liver | 4.3 (0.5)b | 3.6 (0.3)b | 3.9 (1.5) | 4.3 (0.9) |
| Spleen | 5.1 (0.4) | 4.8 (0.4) | 5.0 (1.5) | 5.1 (0.5) |
a
Values are the averages of five inoculated animals, except for the intragastric-inoculation day-2 data, which represent the averages of four animals (one animal was excluded from each group because fewer bacteria than the detection limit [10 CFU/g for liver and <102 CFU/g for spleen] were recovered).
b
Bacterial numbers differ significantly at P = 0.029.
c
Bacterial numbers differ significantly at P = 0.027.