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. 2023 Dec 7;14:1288699. doi: 10.3389/fimmu.2023.1288699

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Copyright © 2023 Wang, Hu, Pei, Zeng and Yao

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Identification of candidate hub genes based the WGCNA analysis. (A) The soft threshold power(left) and mean connectivity(right) of WGCNA network. (B) The cluster dendrogram of WGCNA network. (C) The dot plot showing the top enriched reactome pathways among different modules. (D) The heatmap depicting the relationship between the modules and clinical traits, specifically lupus nephritis and normal controls. (E) The bar chart illustrating the gene significance among different modules in lupus nephritis. (F) The scatter plot between gene significance (GS) and module members (MM) in turquoise module. (G) The venn diagram of the intersection of DEGs, turquoise module genes.