Table 2.
Tumor-derived exosomes as diagnostic biomarkers
| Cancer | Source | Biomarker | Number | Reg. NO |
|---|---|---|---|---|
| Gastric | Plasma | Exosome | 80 | NCT01779583 |
| Cancer | Serum | MiR-15b-3p | Wei et al., 2020155 | |
| Hepatocellular | Serum | miRNA-21 | Lee et al., 2019156 | |
| Carcinoma | Urine | Phospholipid | ChiCTR2200065653 | |
| Colorectal | Serum | Has-circ-0004771 | Pan et al., 2019157 | |
| Cancer | Blood | EXOSCOL01 | 80 | NCT04394572 |
| Non-small cell | Plasma | CD63; EGFR; | Fan et al., 2020158 | |
| Lung Cancer | Blood | CD8+; EGFR | ChiCTR2200061697 | |
| Plasma | 150 | NCT05587114 | ||
| Serum | LncRNA | 1000 | NCT03830619 | |
| Small Cell | Plasma | Non-coding RNA | ChiCTR2200064246 | |
| Lung Cancer | ||||
| Prostatic | Urine | MiR-196a | Rodríguez et al., 2017159 | |
| Cancer | ||||
| Cholangiocarcinoma | Plasma | NcRNA | 80 | NCT03102268 |
| Ovarian Cancer | Plasma | CA125; CD24 | 90 | Im et al., 2014160 |
| Breast Cancer | Blood | CA153 | 90 | Wang et al., 2017161 |
| Plasma | 100 | NCT01344109 | ||
| Osteosarcoma | Blood | RNA | 50 | NCT03108677 |
| Clear cell | Urine | CD9+ | 74 | NCT04053855 |
| Renal Cancer | ||||
| Thyroid | Urine | Thyroglobulin | 30 | NCT05463107 |
| Cancer | Urine | Galectin −3 | NCT03488134 | |
| Saliva | HPV | NCT02147418 | ||
| Oropharyngeal Cancer |