Table 2.
Maternal outcomes
| PPCM | Controls | |
|---|---|---|
| n = 221 | n = 2210 | |
| All-cause death | ||
| Number | 17 | 15 |
| % (95% CI) | 7.7 (4.8–12.1) | 0.7 (0.4–1.1) |
| Rate per 1000 person-years (95% CI) | 8.9 (5.5–14.3) | 0.7 (0.4–1.2) |
| Rate ratio (95% CI) | 11.98 (5.98–23.99) | |
| All-cause rehospitalization | ||
| Number | 166 | 971 |
| % (95% CI) | 75.1 (69.0–80.4) | 44.1 (42.1–46.2) |
| Rate per 1000 person-years (95% CI) | 243.6 (206.2–283.6) | 72.6 (68.1–77.3) |
| Rate ratio (95% CI) | 3.36 (2.58–4.36) | |
| CV rehospitalization | ||
| Number | 89 | 101 |
| % (95% CI) | 40.3 (34.0–46.9) | 4.6 (3.8–5.5) |
| Rate per 1000 person-years (95% CI) | 70.1 (57.0–86.3) | 5.2 (4.2–6.3) |
| Rate ratio (95% CI) | 13.58 (10.22–18.06) | |
| All-cause death or CV rehospitalization | ||
| Number | 96 | 115 |
| % (95% CI) | 43.4 (37.0–50.1) | 5.2 (4.4–6.2) |
| Rate per 1000 person-years (95% CI) | 75.6 (61.9–92.4) | 5.9 (4.9–7.1) |
| Rate ratio (95% CI) | 12.87 (9.81–16.87) | |
| Subsequent stroke or thromboembolism | ||
| Number | 15 | 7 |
| % (95% CI) | 6.8 (4.1–11.0) | 0.3 (0.2–0.7) |
| Rate per 1000 person-years (95% CI) | 8.2 (5.0–13.7) | 0.3 (0.2–0.7) |
| Rate ratio (95% CI) | 23.79 (9.70–58.34) | |
| All-cause death, IABP, VAD, ECMO, or cardiac transplantation | ||
| Number | 30 | - |
| % (95% CI) | 13.6 (9.6–18.8) | - |
| Rate per 1000 person-years (95% CI) | 16.4 (11.5–23.5) | - |
| Intra-aortic balloon pump | ||
| Number | 16 | - |
| % (95% CI) | 7.2 (4.5–11.5) | - |
| VAD, ECMO or cardiac transplantation | ||
| Number | 8 | - |
| % (95% CI) | 3.6 (1.8–7.1) | - |
| Device therapya (n = 218) | ||
| Number | 20 | - |
| % (95% CI) | 9.2 (6.0–13.8) | - |
| CRT | ||
| Number | 7 | - |
| % (95% CI) | 3.2 (1.5–6.6) | - |
| ICD | ||
| Number | 18 | - |
| % (95% CI) | 8.3 (5.3–12.8) | - |
| ICD type | ||
| Primary prevention—number (%) | 11 (61.1) | - |
| Secondary prevention—number (%) | 7 (38.9) | - |
| Appropriate shock therapy (n = 17 with data) | 5 (29.4) | - |
Outcomes are after diagnosis in women with PPCM and after delivery in controls.
aImplantable cardioverter defibrillator or cardiac resynchronization therapy.
CV, cardiovascular; IABP, intra-aortic balloon pump; VAD, ventricular assist device; ECMO, extracorporeal membrane oxygenation; CRT, cardiac resynchronization therapy; ICD, implantable cardioverter defibrillator.