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. 2023 Aug 11;228(12):1667–1674. doi: 10.1093/infdis/jiad324

Table 1.

Characteristics of the Study Population

Molnupiravir Νirmatrelvir/Ritonavir
Recipients Nonrecipients Recipients Nonrecipients
No. % No. % No. % No. %
Outcome
No hospitalization, clinical deterioration, or COVID-19-associated deaths 4022 94.86 3725 87.85 13 462 97.12 12 728 91.83
Hospitalization without ICU admission, clinical deterioration, or death 149 3.51 357 8.42 297 2.14 857 6.18
ICU admission or clinical deterioration 18 0.42 14 0.33 14 0.10 17 0.12
COVID-19–associated death 51 1.20 144 3.40 88 0.63 259 1.87
Hospitalization, ICU admission, clinical deterioration, or death 218 5.14 515 12.14 399 2.88 1133 8.17
Vaccination status
Unvaccinated 534 12.6 859 20.3 1312 9.5 2074 15.0
Single dose 61 1.4 62 1.5 53 0.4 37 0.3
Two doses: before index SARS-CoV-2 infection
 ≤6 mo 220 5.2 426 10.0 458 3.3 657 4.7
 >6 mo 66 1.6 85 2.0 294 2.1 412 3.0
First booster: before index SARS-CoV-2 infection
 ≤6 mo 3318 78.3 2800 66.0 3533 25.5 3745 27.0
 >6 mo 6 0.1 2 0.0 5906 42.6 5681 41.0
Second booster 35 0.8 6 0.1 2305 16.6 1255 9.1
Gender
Male 2128 50.2 2129 50.2 6671 48.1 6462 46.6
Female 2112 49.8 2111 49.8 7190 51.9 7399 53.4
Age, y
65–69 787 18.6 787 18.6 2775 20.0 2775 20.0
70–74 903 21.3 903 21.3 2958 21.3 2958 21.3
75–79 817 19.3 817 19.3 2930 21.1 2930 21.1
≥80 1733 40.9 1733 40.9 5198 37.5 5198 37.5

Abbreviation: ICU, intensive care unit.