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. 2023 Oct 17;86(6):363–376. doi: 10.1159/000533397

Table 2.

Details of verified hub genes

Gene symbol GeneCards identifier Full name Gene-related diseases
CCL2 GC17P034255 C-C motif chemokine ligand 2 Neural tube defects, human immunodeficiency virus type 1, arteriosclerosis, severe acute respiratory syndrome, proliferative glomerulonephritis
GFAP GC17M044917 Glial fibrillary acidic protein Alexander disease, central neurocytoma, astroblastoma, myxopapillary ependymoma, gliomatosis cerebri
CD44 GC11P035139 CD44 molecule Superficial keratitis, intraductal papilloma, acute monoblastic leukemia, malignant pleural mesothelioma, congenital dyserythropoietic anemia
NEFM GC08P024913 Neurofilament medium chain Charcot-Marie-Tooth disease, motor neuron disease, Down syndrome, Wallerian degeneration
STXBP1 GC09P127590 Syntaxin-binding protein 1 Developmental and epileptic encephalopathy 4, infantile epilepsy syndrome, tremor, STXBP1-related encephalopathy, West syndrome
TCEAL6 GC0XM102139 Transcription elongation factor A like 6 Severe congenital neutropenia 7, Pelizaeus-Merzbacher disease, hypomyelinating leukodystrophy