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Immunohistochemistry (IHC) of an ultimobranchial cyst in a 9-y-old horse. A. Positive TTF-1 reactivity in cell nucleus and cytoplasm. IHC. B. Negative anti-thyroglobulin reactivity for the cuboidal cells. IHC. C. TTF-1 positive control. IHC. D. Thyroglobulin positive control. IHC.