Table 2.
Urban—underserved | Urban | Urban—advantaged | Rural—underserved | Rural | Rural—advantaged | Other * | P-value | ||
---|---|---|---|---|---|---|---|---|---|
N | 209 | 699 | 970 | 29 | 265 | 172 | 101 | ||
Mean age (years) | 43.3 ± 16.8 | 46.7 ± 17.5 | 46.6 ± 17.6 | 52.2 ± 15.8 | 49.8 ± 16.8 | 48.7 ± 16.1 | 43.5 ± 17.9 | <.001 | |
Sex | Male | 100 (47.8%) | 336 (48.1%) | 447 (46.1%) | 14 (48.3%) | 119 (44.9%) | 74 (43.0%) | 46 (45.5%) | .911 |
BMI | 28.6 ± 7.5 | 28.1 ± 6.5 | 27.3 ± 6.2 | 32.6 ± 6.2 | 29.0 ± 7.5 | 28.7 ± 5.8 | 27.1 ± 6.6 | <.001 | |
Diagnosis | Crohn’s disease | 141 (67.5%) | 467 (66.8%) | 549 (56.6%) | 19 (65.5%) | 156 (58.9%) | 114 (66.3%) | 68 (67.3%) | |
Ulcerative colitis | 68 (32.5%) | 230 (32.9%) | 419 (43.2%) | 10 (34.5%) | 109 (41.1%) | 56 (32.6%) | 33 (32.7%) | .001 | |
Other | 0 (0.0%) | 2 (0.3%) | 2 (0.2%) | 0 (0.0%) | 0 (0.0%) | 2 (1.2%) | 0 (0.0%) | ||
Mean IBD duration (years) | 13.5 ± 11.1 | 16.4 ± 12.9 | 14.5 ± 12.6 | 12.8 ± 12.5 | 13.9 ± 12.1 | 16.3 ± 13.0 | 13.0 ± 10.8 | .002 | |
IBD treatment | 5-ASA | 39 | 126 | 328 | 8 | 92 | 34 | 15 | |
AZA or monotherapy | 13 | 47 | 79 | 5 | 19 | 12 | 8 | ||
MTX monotherapy | 4 | 6 | 9 | 0 | 4 | 1 | 2 | ||
anti-TNF monotherapy | 70 | 199 | 247 | 6 | 77 | 51 | 32 | ||
anti-TNF + AZA/6-MP | 23 | 70 | 65 | 2 | 22 | 14 | 8 | ||
anti-TNF + MTX | 4 | 12 | 22 | 0 | 6 | 2 | 1 | ||
Vedolizumab monotherapy | 22 | 95 | 101 | 3 | 25 | 17 | 9 | ||
Vedolizumab + AZA/6-MP | 2 | 9 | 10 | 0 | 6 | 2 | 0 | ||
Vedolizumab + MTX | 0 | 3 | 2 | 0 | 2 | 1 | 0 | ||
Ustekinumab | 27 | 80 | 70 | 4 | 19 | 22 | 13 | ||
Ustekinumab + AZA/6-MP | 4 | 17 | 11 | 0 | 1 | 0 | 2 | ||
Ustekinumab + MTX | 1 | 3 | 6 | 1 | 0 | 1 | 1 | ||
Tofacitinib | 1 | 15 | 21 | 0 | 3 | 4 | 3 | ||
Corticosteroid | 25 | 98 | 181 | 7 | 56 | 27 | 22 | ||
Immunosuppressed | Yes | 157 (75.1%) | 546 (78.1%) | 681 (70.2%) | 24 (82.8%) | 196 (74.0%) | 132 (76.7%) | 86 (85.1%) | .001 |
Abbreviations: 5-ASA: 5-aminosalicylic acid; 6-MP: 6-mercaptopurine; AZA: azathioprine; anti-TNF: anti-tumor necrosis factor; MTX: methotrexate.
*Other includes those ZIP codes that had only PO boxes, commercial or organization ZIP codes, or populations less than 500.
ZIP code tabulation areas are derived from Wisconsin Collaborative for Healthcare Quality and the University of Wisconsin Health Innovation Program. Wisconsin Health Disparities Report: Rural and Urban Populations, 2020. https://www.wchq.org/disparities.
The Wisconsin Zip code tabulation areas and their corresponding categories can be downloaded at https://www.hipxchange.org/RuralUrbanGroups.