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. 2023 Dec 14;5(4):otad078. doi: 10.1093/crocol/otad078

Table 2.

Demographics table for ZIP code tabulation areas.

Urban—underserved Urban Urban—advantaged Rural—underserved Rural Rural—advantaged Other * P-value
N 209 699 970 29 265 172 101
Mean age (years) 43.3 ± 16.8 46.7 ± 17.5 46.6 ± 17.6 52.2 ± 15.8 49.8 ± 16.8 48.7 ± 16.1 43.5 ± 17.9 <.001
Sex Male 100 (47.8%) 336 (48.1%) 447 (46.1%) 14 (48.3%) 119 (44.9%) 74 (43.0%) 46 (45.5%) .911
BMI 28.6 ± 7.5 28.1 ± 6.5 27.3 ± 6.2 32.6 ± 6.2 29.0 ± 7.5 28.7 ± 5.8 27.1 ± 6.6 <.001
Diagnosis Crohn’s disease 141 (67.5%) 467 (66.8%) 549 (56.6%) 19 (65.5%) 156 (58.9%) 114 (66.3%) 68 (67.3%)
Ulcerative colitis 68 (32.5%) 230 (32.9%) 419 (43.2%) 10 (34.5%) 109 (41.1%) 56 (32.6%) 33 (32.7%) .001
Other 0 (0.0%) 2 (0.3%) 2 (0.2%) 0 (0.0%) 0 (0.0%) 2 (1.2%) 0 (0.0%)
Mean IBD duration (years) 13.5 ± 11.1 16.4 ± 12.9 14.5 ± 12.6 12.8 ± 12.5 13.9 ± 12.1 16.3 ± 13.0 13.0 ± 10.8 .002
IBD treatment 5-ASA 39 126 328 8 92 34 15
AZA or monotherapy 13 47 79 5 19 12 8
MTX monotherapy 4 6 9 0 4 1 2
anti-TNF monotherapy 70 199 247 6 77 51 32
anti-TNF + AZA/6-MP 23 70 65 2 22 14 8
anti-TNF + MTX 4 12 22 0 6 2 1
Vedolizumab monotherapy 22 95 101 3 25 17 9
Vedolizumab + AZA/6-MP 2 9 10 0 6 2 0
Vedolizumab + MTX 0 3 2 0 2 1 0
Ustekinumab 27 80 70 4 19 22 13
Ustekinumab + AZA/6-MP 4 17 11 0 1 0 2
Ustekinumab + MTX 1 3 6 1 0 1 1
Tofacitinib 1 15 21 0 3 4 3
Corticosteroid 25 98 181 7 56 27 22
Immunosuppressed Yes 157 (75.1%) 546 (78.1%) 681 (70.2%) 24 (82.8%) 196 (74.0%) 132 (76.7%) 86 (85.1%) .001

Abbreviations: 5-ASA: 5-aminosalicylic acid; 6-MP: 6-mercaptopurine; AZA: azathioprine; anti-TNF: anti-tumor necrosis factor; MTX: methotrexate.

*Other includes those ZIP codes that had only PO boxes, commercial or organization ZIP codes, or populations less than 500.

ZIP code tabulation areas are derived from Wisconsin Collaborative for Healthcare Quality and the University of Wisconsin Health Innovation Program. Wisconsin Health Disparities Report: Rural and Urban Populations, 2020. https://www.wchq.org/disparities.

The Wisconsin Zip code tabulation areas and their corresponding categories can be downloaded at https://www.hipxchange.org/RuralUrbanGroups.