TABLE 1.
Characteristics of Patients in the Study Population, Derivation Cohort A and Validation Cohort B
| Characteristics | Study Population (n = 387) |
Derivation Cohort A (n = 274) | Validation Cohort B (n = 113) | P |
|---|---|---|---|---|
| Recipient age (years) Gender (male, %) BMI |
46.7 ± 9.4 344 (88.8 %) 25.78 ± 6.2 |
47.2 ± 9.5 245 (89.4) 25.62 ± 5.4 |
45.6 ± 9.1 99 (87.6) 24.54 ± 6.45 |
0.14 0.60 0.09 |
| Donor age (years) Gender (male, %) Liver attenuation index Steatotic graft |
30.6 ± 9.2 160 (41.3%) 10.78 ± 6.5 42 (10.8%) |
31.1 ± 9.4 115 (42) 10.56 ± 6.4 27 (9.8%) |
29.5 ± 8.5 45 (60.2) 9.68 ± 5.5 15 (13.3%) |
0.12 0.69 0.20 0.32 |
| MELD score at transplant | 23.8 ± 6.1 | 22.9 ± 7.8 | 24.4 ± 6.6 | 0.08 |
| Child-Pugh status A/B (%) | 48 (12.4) | 37 (13.5) | 11 (9.7) | 0.30 |
| C (%) | 339 (86.4%) | 237 (86.5) | 102 (90.3) | |
| Comorbidity (%) | 179 (46.2) | 131 (47.8) | 48 (42.4) | 0.34 |
| Presence of PVT (%) | 44 (11.4%) | 36 (13.1) | 8 (7.1) | 0.08 |
| Anhepatic phase (min) | 136 ± 44.7 | 138 ± 44.3 | 134.4 ± 45.8 | 0.47 |
| Cold ischemia time (min) | 99.8 ± 39.6 | 98.2 ± 31.1 | 103.8 ± 55.1 | 0.20 |
| Warm ischemia time (min) | 30.7 ± 10.8 | 31.3 ± 11 | 29.4 ± 10.1 | 0.11 |
| Graft type (%) | ||||
| Right Left |
330 (85.2%) 57 (14.8%) |
232 (84.7) 42 (15.3) |
98 (86.7) 15 (13.3) |
0.60 |
| Estimated graft weight (grams) | 682.13 ± 129.80 | 679.53 ± 122.29 | 688.45 ± 146.82 | 0.54 |
| GRWR% | 0.98 ± 0.23 | 0.98 ± 0.23 | 0.99 ± 0.24 | 0.77 |
| GRWR<0.8% | 78 (20.2%) | 56 (20.4%) | 22 (19.5%) | 0.83 |
| Portal venous flow (L/min) | 2.7 ± 1.1 | 2.77 ± 1.10 | 2.8 ± 1.16 | 0.72 |
| Blood loss (mL) | 2676 ± 1638 | 2644.8 ± 1551 | 2752.4 ± 1837.3 | 0.55 |
BMI = body mass index; GRWR = graft-to-recipient weight ratio (calculated by estimated graft weight); MELD = model for end-stage liver disease; PVT = portal vein thrombosis.