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. Author manuscript; available in PMC: 2023 Dec 21.
Published in final edited form as: J Hepatol. 2023 May 8;79(3):853–866. doi: 10.1016/j.jhep.2023.04.033

Table 3.

Proportion of patients with AIH with positive autoantibodies compared with their prevalence among healthy population.

Test: antibodies % positive in AIH cases % positive in ‘normal’ population
ANA 1:60 68%–75% 15% (<40 ♀) – 24% (>40 ♀)
ASMA 52%–59% Up to 43%
IgG >1,600 mg/dl 86% 5%
Anti-LKM 4%–20% 1%

AIH, autoimmune hepatitis; ANA, anti-nuclear antibody; anti-LKM, anti-liver-kidney microsomal antibody; ASMA, anti-smooth muscle antibody; DILI, drug-induced liver injury. Adapted from reference 2.