Table 3.
Proportion of patients with AIH with positive autoantibodies compared with their prevalence among healthy population.
Test: antibodies | % positive in AIH cases | % positive in ‘normal’ population |
---|---|---|
ANA 1:60 | 68%–75% | 15% (<40 ♀) – 24% (>40 ♀) |
ASMA | 52%–59% | Up to 43% |
IgG >1,600 mg/dl | 86% | 5% |
Anti-LKM | 4%–20% | 1% |
AIH, autoimmune hepatitis; ANA, anti-nuclear antibody; anti-LKM, anti-liver-kidney microsomal antibody; ASMA, anti-smooth muscle antibody; DILI, drug-induced liver injury. Adapted from reference 2.