TABLE 4.

Screening for advanced fibrosis in high-risk populations

Screening recommendeda	Prevalence of advanced fibrosis, %	References
T2DM	6–19	[10,112,113,115,118,280–284]
Medically complicated obesity	4–33	[256–262,473–480]
NAFLD in context of moderate alcohol use	17	[285–291,300–307]
First-degree relative of a patient with cirrhosis due to NAFLD/NASH	18	[292,293]

Abbreviation: T2DM, type 2 diabetes mellitus.

^aPrevalence of advanced fibrosis in background population 0.9%-2%.^{[14,302,303,305]}