Table I.

Results of recent (2017-present) cohort studies of the prevalence and incidence of OA

Joint(s)	Cohort/Data Source	Country	Age Group	OA Definition(s)	Findings
Any Joint
	EPISER-2016	Spain	≥50 years	Screening questions based on ACR clinical criteria – hand, hip, knee or spine OA	Weighted prevalence of self-reported OA: 29.3% (weights based on probability of selection in each sampling stage)
	Clinical Practice Research Datalink	United Kingdom	≥20 years	General practitioner diagnosis of OA from electronic medical records	Age- and sex-standardized: 6.8 cases of OA per 1000 person years, prevalence of OA: 10.7%
	Clinical Practice Research Datalink	United Kingdom	≥45 years	General practitioner diagnosis of OA from electronic medical records	Annual age- and sex-adjusted rate for clinical OA: 29.2 per 1000 person years in 1992, 40.5 (95% CI 40.3, 40.7) per 1000 person years in 2013
Knee
	Korean National Health and Nutrition Examination Survey	Korea	≥50 years	KL Grade ≥2	Weighted prevalence of radiographic knee OA: 35.1% (weights from sampling and response rates and age/sex proportions of 2005 Korean National Census Registry)
	Chingford Study (Women)	United Kingdom	45–64 years	Incident typical OA: KL 0 to 1, 0 to 2, 1 to 2 Incident accelerated OA: KL 0 to 3	Cumulative 5-year incidence of typical knee OA: 17.6% Cumulative 5-year incidence of accelerated knee OA: 3.7%
	EPISER-2016	Spain	≥40 years	ACR clinical and radiological criteria	Weighted prevalence of symptomatic knee OA: 13.8% (weights based on probability of selection in each sampling stage)
	Clinical Assessment Study of the Knee, Clinical Assessment Study of the Hand, and Clinical Assessment Study of the Foot	United Kingdom	≥50 years	Radiographic evidence plus self-reported pain in the past 4 weeks	Weighted prevalence of radiographic, symptomatic knee OA: 17.4% (weights accounted for initial selective non-response, age, gender, and practice location)
Hip
	EPISER-2016	Spain	≥40 years	ACR clinical and radiological criteria	Weighted prevalence of symptomatic hip OA: 5.1% (weights based on probability of selection in each sampling stage)
	Research on Osteoarthritis/osteoporosis Against Disability	Japan	≥23 years	KL Grade ≥2	Incidence rate of radiographic hip OA: 5.6 per 1,000 person years for men and 8.4 per 1,000 person years in women
Hand
	Clinical Assessment Study of the Knee, Clinical Assessment Study of the Hand, and Clinical Assessment Study of the Foot	United Kingdom	≥50 years	Radiographic evidence plus self-reported pain in the past 4 weeks	Weighted -prevalence of radiographic, symptomatic hand OA: 22.4% (weights accounted for initial selective non-response, age, gender, and practice location)
	EPISER-2016	Spain	≥ 40 years	ACR clinical criteria	Weighted prevalence of symptomatic hand OA: 7.7% (weights based on probability of selection in each sampling stage)
	Johnston County Osteoarthritis Study	United States	≥ 45 years	KL Grade ≥2 in at least one hand joint	Incidence of radiographic hand OA (average 12-year period): 60.5% Incidence of symptomatic hand OA (average 12-year period): 12.9%
	Johnston County Osteoarthritis Study	United States	≥ 45 years	KL grade ≥2 in at least three total joints in each hand (excluding metacarpophalangeal (joints) and at least one affected distal interphalangeal joint plus self-reported pain, aching or stiffness on most days	Lifetime risk of symptomatic hand OA: 39.8% (sampling weights applied based on selection probability, nonresponse adjustments, and post-stratification adjustment)
Foot and Ankle
	Clinical Assessment Study of the Foot	United Kingdom	≥ 50 years	KL Grade ≥2 plus pain in the same ankle	Weighted radiographic, symptomatic ankle OA: 3.4% (weights accounted for initial selective non-response)
	Clinical Assessment Study of the Knee, Clinical Assessment Study of the Hand, and Clinical Assessment Study of the Foot	United Kingdom	≥50 years	Radiographic evidence plus self-reported pain in the past 4 weeks	Weighted prevalence of radiographic, symptomatic foot OA: 16.5% (weights accounted for initial selective non-response, age, gender, and practice location)
	Clinical Practice Research Datalink	United Kingdom	≥20 years	General practitioner diagnosis of OA from electronic medical records	Age- and sex-standardized Incidence of ankle and foot OA: 0.2 per 1,000 person years
	Johnston County Osteoarthritis Project	United States	≥50 years	Score of two or more for osteophytes or joint space narrowing in at least one of five joint sites plus foot pain on most days of any month in the past 12 months	Prevalence of radiographic foot OA: 22.1% Prevalence of symptomatic foot OA: 5.3%
	Johnston County Osteoarthritis Project	United States	≥55 years	Incident ankle OA: KL Grade ≥1 at follow-up among ankles with baseline KL Grade <1; Progressive ankle OA: ≥1 KL Grade increase at follow-up among ankles with KL Grade ≥one at baseline	Incidence of radiographic ankle OA at 3.5 years: 28.2% Progression of radiographic ankle OA at 3.5 years: 4.0%

ACR = American College of Rheumatology; KL= Kellgren Lawrence; OA = osteoarthritis.

KL Grade ≥2 = definite osteophytes and possible joint space narrowing.

ACR Clinical Criteria available here: https://www.rheumatology.org/Practice-Quality/Clinical-Support/Criteria.