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. 2023 Jun 17;109(1):10–24. doi: 10.1210/clinem/dgad356

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Figure 5. — Effect of interleukin-6 (IL-6), monocyte chemoattractant protein 1 (MCP-1), and tumor necrosis factor-α (TNF-α) on adiponectin secretion in adipose tissue of polycystic ovary syndrome (PCOS) and control women. The graphs depict the log scale means of the absolute adiponectin levels in picograms per milliliter (panels A to C) and the net changes in log adiponectin concentration (panels D to F) secreted by PCOS and control adipocytes in response to incubation with 10 ng/mL IL-6 (A and D), MCP-1 (B and E), and TNF-α (C and F). All values were log-transformed before analysis. Sample numbers (n) per group are indicated for each experiment. Reproduced from Chazenbalk G, et al Regulation of adiponectin secretion by adipocytes in the polycystic ovary syndrome: role of tumor necrosis factor-{alpha}. J Clin Endocrinol Metab. 2010 Feb; 95(2):935-42 with permission from Oxford University Press (70).